Vaccine Information

Feeling Uneasy about getting a COVID-19 Vaccine?

 

It’s natural to wonder if brand new vaccines against a novel coronavirus, developed at unprecedented speeds, are effective and safe to take. Here is what we know:

Overall effectiveness has been reported in the range of 70% to 95%. 

That’s well above the average effectiveness of the flu vaccine.

  • A Moderna vaccine trial enrolling more than 30,000 volunteers reported an effectiveness of 94%.
  • Johnson & Johnson (Janssen) trial reported overall effectiveness of 66% (72% in the US) in preventing moderate to severe COVID-19.

Not only do these vaccines appear to lessen risk of developing COVID-19, 

but they also appear to lessen the risk of severe disease.

 

In large clinical trials, most side effects have been minor. When side effects occur, they typically last just a few days. A side effect or reaction isn’t necessarily all bad, by the way; it may indicate that the body is building protection against the virus.

 

Side Effect

1st Dose

2nd Dose

Pain at the site of the injection

90.1%

94.5%

Painful, swollen lymph nodes in the arm where the vaccine was injected

11.9%

16.6%

Tiredness

39.5%

78.3%

Headache

37.2%

67.8%

Muscle or Joint Aches

24.3%

71.7%

Nausea and Vomiting

9.4%

21.4%

Fever

0.9%

19.2%

Chills

9.3%

50.1%

Most side effects occur within the first 48 hours after vaccination.

 

Most significant side effect: Anaphylaxis          Occurrence: 11 cases per 1 Million Doses

* According to the Centers for Disease Control and Prevention (CDC).

https://www.health.harvard.edu/blog/covid-19-vaccines-safety-side-effects-and-coincidence-2021020821906

 

Franklin County Statistics

As of March 26, 2021

Total Doses Administered:

1st Doses

2nd Doses

Johnson & Johnson

7,315

4,430

2,720

165

 

To date, Franklin County has had 1 report of Anaphylaxis.

The reported case was treated with epinephrine and transported to AdventHealth Ottawa for monitoring. 

 

There have been three individuals treated for vaccine-related issues: two have had a vasovagal response (fainting ) and 1 individual had an anxiety attack.


What is an mRNA Vaccine?

COVID-19 mRNA vaccines give instructions for our cells to make a harmless piece of what is called the “spike protein.” The spike protein is found on the surface of the virus that causes COVID-19. 

*Centers for Disease Control and Prevention

                        

Fact:

The Vaccine cannot give you COVID-19 – mRNA vaccines do not contain live virus.

 

The Vaccine does not affect or interact with our DNA in anyway – mRNA never enter the nucleus of the cell, which is where our DNA (genetic material) is kept.

 

There are rumors that mRNA vaccines will alter our DNA because the RNA molecule can convert information stored in DNA into proteins. That’s simply, not true. It’s critical to note that the mRNA vaccines never enter the nucleus of the cell, where our DNA is stored. After injection, the mRNA from the vaccine is released into the cytoplasm of the cells. Once the viral protein is made and on the surface of the cell, mRNA is broken down and the body permanently gets rid of it, therefore making it impossible to change our DNA.


What is in the Moderna COVID-19 Vaccine?

Messenger ribonucleic acid, mRNA is the only active ingredient in the vaccine. The mRNA molecules contain the genetic material that provide instructions for our body on how to make a viral protein that triggers an immune response within our bodies. The immune response is what causes our bodies to make the antibodies needed to protect us from getting infected if exposed to the coronavirus.

Each 0.5 mL dose of the Moderna COVID-19 Vaccine contains 100 mcg of a nucleoside-modified messenger RNA (mRNA) encoding the viral spike (S) glycoprotein of SARS-CoV-2. Each dose of the Moderna COVID-19 Vaccine also includes the following ingredients:

  • Lipids
  • Cholesterol
  • Tromethamine Hydrochloride {Used for electrolyte imbalance}
  • Acetic Acid
  • Sodium Acetate
  • Sucrose
    *This information is directly from the EUA of the Moderna vaccine

Lipids – protect the mRNA and provide somewhat of a “greasy” exterior that helps the mRNA slide inside the cells. 

The remaining ingredients; acids, acid stabilizers, salt and sugar all work together to maintain the stability of the vaccine after it’s produced.


What is in the Johnson & Johnson COVID-19 Vaccine?

The Janssen COVID-19 Vaccine includes the following ingredients:

  • Recombinant
  • Replication-incompetent adenovirus type 26 expressing the SARS-CoV-2 spike protein
  • citric acid monohydrate
  • trisodium citrate dihydrate
  • ethanol
  • 2-hydroxypropyl-β-cyclodextrin (HBCD)
  • polysorbate-80
  • sodium chloride

J&J uses an adenovirus – a type of virus that causes the common cold, which has been inactivated – to carry a gene from the coronavirus into human cells. The cells then produce coronavirus proteins (not the virus itself) to mimic the virus, which helps prime the immune system to fight off later infection in the body encounters the coronavirus.